H6H (p.His6His) variant of MC4R (Melanocortin receptor 4)
H6H (p.His6His) in MC4R (Melanocortin receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
H6H (p.His6His) variant details
- p.His6His
- rs1915367991
- gnomAD 18-60372332-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.277
- CADD 1.89
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available