G8G (p.Gly8Gly) variant of MC4R (Melanocortin receptor 4)
G8G (p.Gly8Gly) in MC4R (Melanocortin receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
G8G (p.Gly8Gly) variant details
- p.Gly8Gly
- rs148256915
- gnomAD 18-60372326-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.113
- CADD 4.62
- Most common in the African/African-American population (allele frequency 0.00022)
- Structural context available
- Literature evidence available