G32E (p.Gly32Glu) variant of MC4R (Melanocortin receptor 4)
G32E (p.Gly32Glu) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G32E (p.Gly32Glu) variant details
- p.Gly32Glu
- ExAC rs778632018
- TOPMed rs778632018
- gnomAD rs778632018
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.04
- MetaLR 0.06
- MetaSVM -1.07
- CADD 12.90
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 9e-06)
- Structural context available