R25K (p.Arg25Lys) variant of MAX (Protein max)
R25K (p.Arg25Lys) in MAX (Protein max) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
R25K (p.Arg25Lys) variant details
- p.Arg25Lys
- rs1595127306
- gnomAD 14-65076623-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.543
- AlphaMissense 0.20
- MetaLR 0.37
- MetaSVM -0.43
- CADD 11.20
- PolyPhen-2 0.99
- MutPred 0.25
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available