V75A (p.Val75Ala) variant of MAPT (P10636)
V75A (p.Val75Ala) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V75A (p.Val75Ala) variant details
- p.Val75Ala
- ExAC rs774890160
- gnomAD rs774890160
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.06
- CADD 12.60
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available