V10M (p.Val10Met) variant of MAPT (P10636)
V10M (p.Val10Met) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
V10M (p.Val10Met) variant details
- p.Val10Met
- TOPMed rs1204505552
- gnomAD rs1204505552
- Missense
- Variant Prioritization Score for Impact Estimate 0.0827
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -0.99
- CADD 1.34
- PolyPhen-2 0.42
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available