T76P (p.Thr76Pro) variant of MAPT (P10636)
T76P (p.Thr76Pro) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
T76P (p.Thr76Pro) variant details
- p.Thr76Pro
- gnomAD 17-45978398-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.17
- MetaLR 0.18
- MetaSVM -0.91
- CADD 27.50
- PolyPhen-2 0.98
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available