T76K (p.Thr76Lys) variant of MAPT (P10636)
T76K (p.Thr76Lys) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T76K (p.Thr76Lys) variant details
- p.Thr76Lys
- 1000Genomes rs578177484
- ExAC rs578177484
- gnomAD rs578177484
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.13
- CADD 25.60
- SIFT 0.02
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available