T76I (p.Thr76Ile) variant of MAPT (P10636)
T76I (p.Thr76Ile) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T76I (p.Thr76Ile) variant details
- p.Thr76Ile
- 1000Genomes rs578177484
- ExAC rs578177484
- gnomAD rs578177484
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.13
- CADD 29.20
- SIFT 0.04
- Most common in the HGDP:MBUTI population (allele frequency 0.083)
- Structural context available