T63A (p.Thr63Ala) variant of MAPT (P10636)
T63A (p.Thr63Ala) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
T63A (p.Thr63Ala) variant details
- p.Thr63Ala
- gnomAD 17-45971912-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.10
- CADD 19.00
- PolyPhen-2 0.05
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available