T17A (p.Thr17Ala) variant of MAPT (P10636)
T17A (p.Thr17Ala) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
T17A (p.Thr17Ala) variant details
- p.Thr17Ala
- gnomAD 17-45962386-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0659
- REVEL 0.01
- MetaLR 0.06
- MetaSVM -1.06
- CADD 0.18
- PolyPhen-2 0.46
- SIFT 0.58
- Population evidence available
- Structural context available
- Literature evidence available