M31I (p.Met31Ile) variant of MAPT (P10636)
M31I (p.Met31Ile) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
M31I (p.Met31Ile) variant details
- p.Met31Ile
- gnomAD rs1214314857
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.08
- CADD 13.50
- PolyPhen-2 0.31
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available