M11V (p.Met11Val) variant of MAPT (P10636)
M11V (p.Met11Val) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
M11V (p.Met11Val) variant details
- p.Met11Val
- gnomAD 17-45962368-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.04
- CADD 11.10
- PolyPhen-2 0.65
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available
- Literature evidence available