K24R (p.Lys24Arg) variant of MAPT (P10636)
K24R (p.Lys24Arg) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
K24R (p.Lys24Arg) variant details
- p.Lys24Arg
- gnomAD 17-45962408-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.06
- CADD 23.00
- PolyPhen-2 0.81
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available