E12E (p.Glu12Glu) variant of MAPT (P10636)
E12E (p.Glu12Glu) in MAPT (P10636) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
E12E (p.Glu12Glu) variant details
- p.Glu12Glu
- rs375852870
- gnomAD 17-45962373-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.11
- CADD 4.14
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available