D74G (p.Asp74Gly) variant of MAPT (P10636)
D74G (p.Asp74Gly) in MAPT (P10636) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
D74G (p.Asp74Gly) variant details
- p.Asp74Gly
- rs2072082663
- gnomAD 17-45974384-GAT-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.875
- CADD 34.00
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available
- Literature evidence available