D74E (p.Asp74Glu) variant of MAPT (P10636)
D74E (p.Asp74Glu) in MAPT (P10636) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
D74E (p.Asp74Glu) variant details
- p.Asp74Glu
- gnomAD 17-45974385-ATGTG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.582
- CADD 31.00
- Population evidence available
- Structural context available
- Literature evidence available