D38G (p.Asp38Gly) variant of MAPT (P10636)
D38G (p.Asp38Gly) in MAPT (P10636) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
D38G (p.Asp38Gly) variant details
- p.Asp38Gly
- gnomAD rs1198505498
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.19
- MetaLR 0.15
- MetaSVM -0.79
- CADD 22.90
- PolyPhen-2 0.92
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available