D22G (p.Asp22Gly) variant of MAPT (P10636)
D22G (p.Asp22Gly) in MAPT (P10636) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
D22G (p.Asp22Gly) variant details
- p.Asp22Gly
- gnomAD 17-45962396-T-TG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.32
- CADD 23.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available