V49D (p.Val49Asp) variant of MAPK1 (P28482)
V49D (p.Val49Asp) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
V49D (p.Val49Asp) variant details
- p.Val49Asp
- TOPMed rs2069154803
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.30
- CADD 22.90
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- MAPK1 DOX: score 7.24