V18G (p.Val18Gly) variant of MAPK1 (P28482)
V18G (p.Val18Gly) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, experimental measurements, and structural context.
V18G (p.Val18Gly) variant details
- p.Val18Gly
- Ensembl rs2145760387
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.27
- CADD 23.10
- PolyPhen-2 0.03
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 5.7e-06)
- Structural context available
- MAPK1 VRT-11E: score 5.86