V14F (p.Val14Phe) variant of MAPK1 (P28482)
V14F (p.Val14Phe) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, experimental measurements, and structural context.
V14F (p.Val14Phe) variant details
- p.Val14Phe
- TOPMed rs1349430059
- gnomAD rs1349430059
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.53
- CADD 25.20
- PolyPhen-2 0.78
- SIFT 0.01
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available
- MAPK1 SCH772984: score 6.94