R91Q (p.Arg91Gln) variant of MAPK1 (P28482)
R91Q (p.Arg91Gln) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, and structural context.
R91Q (p.Arg91Gln) variant details
- p.Arg91Gln
- TOPMed rs2069153764
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.30
- CADD 23.50
- PolyPhen-2 0.21
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- MAPK1 VRT-11E: score 6.37