R148H (p.Arg148His) variant of MAPK1 (P28482)
R148H (p.Arg148His) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data, experimental measurements, and structural context.
R148H (p.Arg148His) variant details
- p.Arg148His
- cosmic curated COSV53185
- ExAC rs749425404
- TOPMed rs749425404
- gnomAD rs749425404
- Missense
- Variant Prioritization Score for Impact Estimate 0.709
- REVEL 0.64
- CADD 29.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- MAP1K ETP: score 8.92