P11T (p.Pro11Thr) variant of MAPK1 (P28482)
P11T (p.Pro11Thr) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, and structural context.
P11T (p.Pro11Thr) variant details
- p.Pro11Thr
- TOPMed rs977423767
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.17
- CADD 21.50
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- MAPK1 SCH772984: score 6.56