N45S (p.Asn45Ser) variant of MAPK1 (P28482)
N45S (p.Asn45Ser) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
N45S (p.Asn45Ser) variant details
- p.Asn45Ser
- TOPMed rs1008537544
- gnomAD rs1008537544
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.07
- CADD 20.50
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- MAPK1 DOX: score 7.23