M38L (p.Met38Leu) variant of MAPK1 (P28482)
M38L (p.Met38Leu) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
M38L (p.Met38Leu) variant details
- p.Met38Leu
- Ensembl rs2145760296
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.25
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available
- MAPK1 VRT-11E: score 8.21