L107F (p.Leu107Phe) variant of MAPK1 (P28482)
L107F (p.Leu107Phe) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, experimental measurements, and structural context.
L107F (p.Leu107Phe) variant details
- p.Leu107Phe
- Ensembl rs2148655450
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.45
- CADD 24.50
- PolyPhen-2 0.08
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- MAPK1 VRT-11E: score 6.27