I133V (p.Ile133Val) variant of MAPK1 (P28482)
I133V (p.Ile133Val) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
I133V (p.Ile133Val) variant details
- p.Ile133Val
- gnomAD rs1453621955
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.20
- CADD 22.90
- PolyPhen-2 0.36
- SIFT 0.12
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- MAPK1 DOX: score 7.25