G16W (p.Gly16Trp) variant of MAPK1 (P28482)
G16W (p.Gly16Trp) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G16W (p.Gly16Trp) variant details
- p.Gly16Trp
- gnomAD rs1213398032
- Missense
- Variant Prioritization Score for Impact Estimate 0.651
- REVEL 0.73
- CADD 28.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00014)
- Structural context available
- MAPK1 SCH772984: score 5.4