F19L (p.Phe19Leu) variant of MAPK1 (P28482)
F19L (p.Phe19Leu) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, and structural context.
F19L (p.Phe19Leu) variant details
- p.Phe19Leu
- 1000Genomes rs749142638
- ExAC rs749142638
- gnomAD rs749142638
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.23
- CADD 25.70
- PolyPhen-2 0.44
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.5e-05)
- Structural context available
- MAPK1 SCH772984: score 5.11