E96K (p.Glu96Lys) variant of MAPK1 (P28482)
E96K (p.Glu96Lys) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E96K (p.Glu96Lys) variant details
- p.Glu96Lys
- 1000Genomes rs530183395
- ExAC rs530183395
- TOPMed rs530183395
- gnomAD rs530183395
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.13
- CADD 24.90
- PolyPhen-2 0.30
- SIFT 0.04
- Most common in the 1KG:MSL population (allele frequency 0.0063)
- Structural context available
- MAPK1 VRT-11E: score 6.8