E33Q (p.Glu33Gln) variant of MAPK1 (P28482)
E33Q (p.Glu33Gln) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E33Q (p.Glu33Gln) variant details
- p.Glu33Gln
- cosmic curated COSV53185
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.27
- CADD 23.60
- PolyPhen-2 0.76
- SIFT 0.08
- Population evidence available
- Structural context available
- MAPK1 VRT-11E: score 5.44