E12G (p.Glu12Gly) variant of MAPK1 (P28482)
E12G (p.Glu12Gly) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E12G (p.Glu12Gly) variant details
- p.Glu12Gly
- cosmic curated COSV10956
- Ensembl rs2145760432
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.40
- CADD 28.80
- PolyPhen-2 0.87
- SIFT 0.04
- Population evidence available
- Structural context available
- MAPK1 SCH772984: score 5.22