D44Y (p.Asp44Tyr) variant of MAPK1 (P28482)
D44Y (p.Asp44Tyr) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, experimental measurements, and structural context.
D44Y (p.Asp44Tyr) variant details
- p.Asp44Tyr
- ExAC rs779189994
- TOPMed rs779189994
- gnomAD rs779189994
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- REVEL 0.62
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available
- MAPK1 SCH772984: score 7.56