A5V (p.Ala5Val) variant of MAPK1 (P28482)
A5V (p.Ala5Val) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A5V (p.Ala5Val) variant details
- p.Ala5Val
- 1000Genomes rs1282708145
- TOPMed rs1282708145
- gnomAD rs1282708145
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.17
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available
- MAPK1 VRT-11E: score 6.72