A5G (p.Ala5Gly) variant of MAPK1 (P28482)
A5G (p.Ala5Gly) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A5G (p.Ala5Gly) variant details
- p.Ala5Gly
- 1000Genomes rs1282708145
- TOPMed rs1282708145
- gnomAD rs1282708145
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.12
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the REMAINING population (allele frequency 2.8e-05)
- Structural context available
- MAPK1 VRT-11E: score 6.72