A4V (p.Ala4Val) variant of MAPK1 (P28482)
A4V (p.Ala4Val) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A4V (p.Ala4Val) variant details
- p.Ala4Val
- Ensembl rs2145760493
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.14
- CADD 21.70
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 2.3e-06)
- Structural context available
- MAPK1 DOX: score 5.53