A3V (p.Ala3Val) variant of MAPK1 (P28482)
A3V (p.Ala3Val) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A3V (p.Ala3Val) variant details
- p.Ala3Val
- Ensembl rs1378179068
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.26
- CADD 24.10
- PolyPhen-2 0.75
- SIFT 0.57
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- MAPK1 VRT-11E: score 6.61