A2V (p.Ala2Val) variant of MAPK1 (P28482)
A2V (p.Ala2Val) in MAPK1 (P28482) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A2V (p.Ala2Val) variant details
- p.Ala2Val
- cosmic curated COSV53187
- Ensembl rs2145760505
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.21
- CADD 23.40
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.3e-06)
- Structural context available
- MAPK1 VRT-11E: score 5.57