V8M (p.Val8Met) variant of MAP2K2 (P36507)
V8M (p.Val8Met) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
V8M (p.Val8Met) variant details
- p.Val8Met
- ExAC rs779834046
- gnomAD rs779834046
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.26
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.13
- Population evidence available
- Structural context available