V35M (p.Val35Met) variant of MAP2K2 (P36507)
V35M (p.Val35Met) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V35M (p.Val35Met) variant details
- p.Val35Met
- gnomAD rs1057519810
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.33
- CADD 23.70
- PolyPhen-2 0.53
- SIFT 0.14
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available