V35L (p.Val35Leu) variant of MAP2K2 (P36507)
V35L (p.Val35Leu) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V35L (p.Val35Leu) variant details
- p.Val35Leu
- gnomAD rs1057519810
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.27
- CADD 21.20
- PolyPhen-2 0.07
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.4e-05)
- Structural context available