T17I (p.Thr17Ile) variant of MAP2K2 (P36507)
T17I (p.Thr17Ile) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T17I (p.Thr17Ile) variant details
- p.Thr17Ile
- gnomAD rs1380162746
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.10
- AlphaMissense 0.27
- MetaLR 0.25
- MetaSVM -0.77
- CADD 18.80
- PolyPhen-2 0.38
- Most common in the South Asian population (allele frequency 3.7e-05)
- Structural context available