S23P (p.Ser23Pro) variant of MAP2K2 (P36507)
S23P (p.Ser23Pro) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S23P (p.Ser23Pro) variant details
- p.Ser23Pro
- Ensembl rs2145089801
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.25
- CADD 24.40
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available