R5S (p.Arg5Ser) variant of MAP2K2 (P36507)
R5S (p.Arg5Ser) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R5S (p.Arg5Ser) variant details
- p.Arg5Ser
- Ensembl rs2145090029
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.16
- CADD 23.00
- PolyPhen-2 0.02
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3.2e-05)
- Structural context available