R4P (p.Arg4Pro) variant of MAP2K2 (P36507)
R4P (p.Arg4Pro) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R4P (p.Arg4Pro) variant details
- p.Arg4Pro
- Ensembl rs2145090044
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.30
- CADD 24.20
- PolyPhen-2 0.14
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.2e-05)
- Structural context available