P7S (p.Pro7Ser) variant of MAP2K2 (P36507)
P7S (p.Pro7Ser) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
P7S (p.Pro7Ser) variant details
- p.Pro7Ser
- Ensembl rs587781031
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.27
- CADD 23.80
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the East Asian population (allele frequency 3.1e-05)
- Structural context available