P24L (p.Pro24Leu) variant of MAP2K2 (P36507)
P24L (p.Pro24Leu) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P24L (p.Pro24Leu) variant details
- p.Pro24Leu
- gnomAD rs1420256288
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.16
- AlphaMissense 0.11
- MetaLR 0.29
- MetaSVM -0.57
- CADD 23.50
- PolyPhen-2 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available