P24H (p.Pro24His) variant of MAP2K2 (P36507)
P24H (p.Pro24His) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P24H (p.Pro24His) variant details
- p.Pro24His
- gnomAD rs1420256288
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.21
- AlphaMissense 0.14
- MetaLR 0.32
- MetaSVM -0.44
- CADD 24.20
- PolyPhen-2 0.12
- Most common in the Ashkenazi Jewish population (allele frequency 4e-05)
- Structural context available